Pacific Standard March-April 2013 Cover

Calm Down, Step Away From the Burger

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If it’s true that we are what we eat, then people who eat a lot of trans fatty acids — common in fast foods ­— might be a bit touchier than the rest of us. In a new study of eating habits and behavior, Dr. Beatrice Golomb, a researcher and professor at the University of California, San Diego medical school, lays out evidence that a diet high in trans fats is linked to traits of irritability and aggression. In her study, Golomb gave 945 Californians who had already enrolled in a drug clinical trial a standard dietary questionnaire that asked what they ate and how often they ate ... Read More

Mice Losing Weight With Less Exercise?

What if there was a pill that would allow you to add lean muscle mass and lower your cholesterol and insulin levels, all while chowing down on your favorite high-fat, high-sugar foods? Scripps Research Institute scientists in Florida may have done just that — in mice. The scientists have crafted a pair of synthetic molecules that cause them to lose weight, exercise more, and normalize their blood sugar by tinkering with the “clock” that controls a mouse’s metabolism. The research, published in Nature online, opens the door for new drugs to treat obesity, cardiovascular disease, ... Read More

Obesity Virus, Fat Chickens and Life’s Mysteries

Viruses can make you fat — and your dirty-fingered friends can give these viruses to you. That is the punch line — a known truth about the world. The set-up, though, is longer in the telling. It begins with a boy named Nikhil living in India. When Nikhil Dhurandhar was young, his father directed a large obesity clinic in Bombay. Throughout his childhood, Nikhil saw thousands of his father's obese patients. They came in for some cure, whether salve or salvation. Instead, they received, again and again, the same advice: "Move more. Eat less." It is what doctors around the world tell ... Read More

What We Miss When We Obsess Over Obesity

Obesity

Just as Congress was concluding a contentious year of debate by passing legislation to overhaul the health care system, a revealing look at lifestyle, income and mortality was published in the journal Social Science & Medicine. It followed a cross-section of American adults to determine precisely which factors drive us to an early death. Some of the answers were expected. Cigarette smoking. A sedentary lifestyle. Being poor. One well-publicized issue did not make the list: Obesity. For all the breathless media coverage of our collective weight gain over the past few decades, it turns ... Read More

A Fatter Phobia

You’re at the office, on a budget, it’s almost lunch time and — you’re starving. You can’t go to a grocery store because you have no time to cook (although if you did go, you’d notice that most of the healthier items cost more than the heavily marketed junk). On the way out of the office you walk past a gym and cringe (now you’re likely to inadvertently increase your food consumption at lunch). Finally you reach the outside of McDonald’s, which represents the antithesis of your dieting goals. Secretly you’d like to gorge yourself on a Big Mac, but you stride into the ... Read More

A Spicy Way to Keep the Weight Off?

In a recent study, researchers at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University found that curcumin, the active ingredient in turmeric, seems to reduce weight gain and retard the growth of fat tissue in mice that were fed high-fat diets. Their research is published in the May 2009 issue of the Journal of Nutrition. "Weight gain is the result of the growth and expansion of fat tissue, which cannot happen unless new blood vessels form, a process known as angiogenesis," said senior author Mohsen Meydani, director of the center's Vascular Biology Laboratory, ... Read More

Policy-Heavy Play

Grand Theft Auto: San Andreas" became something of a cyberspace scandal in 2005, when gleeful gamers discovered its graphic sex scenes. But Ian Bogost found himself intrigued by the best-selling video game for another reason entirely. He was fascinated by one of the characters, a thug whose physical appearance was virtually unheard of in the gaming universe. This gangbanger had a gut. "Depending on what and how much he ate, he would get fatter," says the veteran video game designer, a faculty member of the Georgia Institute of Technology. "You could have him work out and get buff. That ... Read More