Pacific Standard July-August 2013 Cover

Body Language

(ILLUSTRATION: DANIEL STOLLE)

Listen to Life in the Data, Episode 2, featuring Daniel Duane: It all started with 229, 178, and 24.8, back in 2006. Before that, I thought of my health in words: surfer, jogger, farmers’-market shopper, nonsmoker, prudent father of two young girls. Put another way, I thought I lived too sensibly to worry about cholesterol. Then I discovered French cooking and home butchery, started buying whole hogs and keeping all those chops in a freezer. Plus, I turned 38. I’m not sure what it was about 38; maybe the view it provided of 40. I decided to get a checkup. That first number, 229, ... Read More

Mice Losing Weight With Less Exercise?

What if there was a pill that would allow you to add lean muscle mass and lower your cholesterol and insulin levels, all while chowing down on your favorite high-fat, high-sugar foods? Scripps Research Institute scientists in Florida may have done just that — in mice. The scientists have crafted a pair of synthetic molecules that cause them to lose weight, exercise more, and normalize their blood sugar by tinkering with the “clock” that controls a mouse’s metabolism. The research, published in Nature online, opens the door for new drugs to treat obesity, cardiovascular disease, ... Read More

New Statin Warnings Include Brain-Related Effects

Since 2009, Miller-McCune has taken a couple bites of the apple surrounding statins – a class of drugs used to lower cholesterol in the bloodstream – and whether there might be some unacknowledged health concerns for some users. Just about anything a human might ingest, from aspirin to water, might prove harmful in some cases, but we looked at statins because they were so popular (in 2009, we estimated 13 million in the U.S. alone were prescribed statins, and that figure is now believed to be north of 20 million) and yet there was little discussion of the drugs’ risks. And there are ... Read More

Statins, Lou Gehrig and Big Questions

Dr. Greg Burns (not his real name) is a 72-year-old retired radiologist living in Connecticut. Until early last year, he ran with his dog at canine agility meets, skied, ice skated and played 18 holes of golf. He is now unable to walk and is taking a course of medication that will postpone, by a few months, his death. Burns' rapid decline began in December 2007 when he suffered a short-acting stroke from which he fully recovered. His cholesterol level was elevated and so as a preventative measure his doctor prescribed a 20mg daily dose of Crestor, a cholesterol-lowering drug in the ... Read More

Warnings About Statins Grow Louder

Statins have been marketed — and widely described in the media — as wonder drugs which help ensure heart health by lowering cholesterol. But as we reported in 2009 ("Cholesterol Contrarians Question Cult of Statins"), an outspoken group of researchers warn their use is too widespread, and their potential dangers underestimated. A study just published in the journal The Cochrane Collaboration suggests their doubts are valid. Researchers from the London School of Hygiene & Tropical Medicine reviewed previous studies on the risks and benefits of statins for people at low risk of ... Read More

Cholesterol Contrarians Question Cult of Statins

The near-breakdown of the international financial system and the deep recession it helped create has been attributed to many causes. Greed, of course. A lack of rigorous regulation. An everyone's-doing-it mentality in which traders took bigger and bigger risks as they search for bigger and bigger payoffs. Now, a Florida physician proposes an alternative explanation. Perhaps many of those supposedly sophisticated speculators who believed the party would never end were acting under the influence of drugs. Cholesterol-lowering drugs. "There's a damn good possibility it's related!" said ... Read More